Camplyobacter like organism (CLO) test

Rapid urease test for Helicobacter pylori infection of the stomach.

Gastric biopsy taken during upper gastrointestinal endoscopy is applied to a dry urea impregnated pad and if H. pylori is present in the stomach the incubated pad produces urea which is hydrolyzed to ammonia gas which changes the color of a pH indictor.

Phenol red dye turns pink when pH is 6.0 or greater.

Only half hour needed for test results which has a 98% sensitivity and 100% specificity.

Invasive test of choice for diagnosis of H. pylori.

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