Buprenorphine transdermal system

Indicated for the management of moderate to severe chronic pain in patients requiring continuous, around-the-clock opioid analgesics for an extended period of time.

A mu opioid partial agonist.

In doses greater than 20 mcg per hour increases the risk of QTc interval prolongation.

Butrans transdermal patch is intended to be worn for 7 days.

Contraindicated in patients with respiratory depression, severe asthma or have paralytic ileus.

Initiation of dosing is individualized.

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