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Bumetamide

Trade name Bumex

Diuretic with oral, intravenous, and intramuscular administration.

Bioavailability almost complete at 80%.

Protein binding of 97%.

Hepatic metabolism.

Half-life of 1-3 hours and is 6 to 8 hour duration of action.

Renal excretion.

A loop diuretic of the sulfamyl category to treat heart failure.

 

It is often used when high doses of furosemide are ineffective. 

Almost completely absorbed.

 

Absorption is not altered when taken with food. 

A more predictable diuretic than furosemide.

40 times more potent than furosemide for patients with normal renal function.

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