Blocks the cytosol transport of testosterone to the nucleus, producing cellular androgen deprivation.
Main side effects breast pain and gynecomastia that occurs in approximately 2 out of 3 patients.
Raises serum testosterone by 70% and serum estradiol levels by 85%.
Pure antiandrogen that acts by blocking the binding of dihydrotestosterone to the androgen receptor.
Thought to have a better safety and biochemical profile than flutamide.
Drug withdrawal can lead to a response in patients with prostate cancer.