Most common abnormal diagnosis reported on Papanicolaou tests in the U.S., with a mean rate of 5.2% and with 10% of laboratories reporting rates >9.9%.
Comprises over 50% of abnormal PAP test results.
Much less likely to have significant disease than patients with AGUS.
Recommended that Pap tests be repeated every 4 to 6 months for 2 years and that coloposcopy be performed only if the Pap test again shows ASCUS during the interval.
Accounts for approximately 7-10% of CIN3 lesions.