A form of joint disorder that involves inflammation of one or more joints.

Arthritic pain has annual direct healthcare expenses of an estimated $81 billion, with indirect costs of $189 billion annually.

There are over 100 different forms of arthritis.

The most common form, osteoarthritis is degenerative joint disease, is the result of trauma, infection of the joint, or age.

Other arthritis forms are rheumatoid arthritis, psoriatic arthritis, and related autoimmune diseases.

Septic arthritis is caused by joint infection.

The major complaint is joint pain, due to inflammation that occurs around the joint and damage to the joint from disease.

Estimated that 21.6% of the adult U.S. population has the diagnosis of arthritis and 8.3% have arthritis that limits activities.

Prevalence higher in women compared with men, 25.4% vs. 17.6%.

Prevalence in individuals older than 65 years is 50%, with 29.3% for persons aged 45-64 years of age, and 7.9% for persons 18-44 years of age.

Up to 15% of newly diagnosed cases of arthritis are due to parvovirus 19 (Corcoran A).

Several diseases where arthritis is considered the main feature and include:


Rheumatoid arthritis

Gout and pseudo-gout

Septic arthritis

Ankylosing spondylitis

Juvenile idiopathic arthritis

Still’s disease

When arthritis is considered to be secondary to the main disease, and these include:

Psoriasis (Psoriatic arthritis)

Reactive arthritis

Ehlers-Danlos Syndrome



Lyme disease

Inflammatory bowel disease

Henoch-Schönlein purpura

Hyperimmunoglobulinemia D with recurrent fever


TNF receptor associated periodic syndrome

Wegener’s granulomatosis and vascularitis syndromes

Familial Mediterranean  fever

Systemic lupus erythematosus

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