Anticoagulant use in pregnancy

Potential fetal complications include teratogenicity, bleeding and fetal loss.

Unfractionated heparin, low-molecular weight heparin, and danaproid do not cross the placenta.

Vitamin K antagonists cross the placenta and have the potential for fetal complications.

If warfarin is taken between weeks associated with nasal hypoplasia, and stippled epiphyses.

Exposure to warfarin during any trimester can be associated with CNS abnormalities.

Maternal complications include: bleeding, heparin induced thrombocytopenia, heparin associated osteoporosis, and pain at the site of injections.

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