A variety of such drugs exist and act on factors that promote the growth of blood vessels necessary for cancers to proliferate and grow.
Agents include bevacizumab,Ziv-aflibercept, ramucirumab, and Regorafenib.
The main side effects of this class of drugs as hypertension, risk of thrombosis, myocardial infarction, or stroke.
Gastrointestinal perforation and hemorrhage are other side effects.
Major complications occurred approximately 1 and 25 patients.