Anesthetic agents

Diminish response to hypercapnea and hypoxia and are associated with alterations in respiratory drive.

In combination with neuromuscular blockers can cause the diaphragm to relax resulting in marked reduction in lung functional reserve capacity.

By decreasing lung volume promotes ateletasis in the dependent lung regions.

Can cause arterial hypoxemia due to ventilation perfusion mismatch and increased shunting.

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