An uncommon, non-sexually transmitted condition characterized by rapid onset of painful, necrotic ulcerations of the vulva or lower vagina.
Clinically lesions are similar in appearance and symptoms of the oral canker sore.
The lesions are sharply marginated in appearance with rolled erythematous borders.
Such ulcers can have a white coagulum initially, and can be up to 3 cm in size.
Differential diagnosis includes Crohn’s disease, herpes simplex virus, trauma, malignancy, pyoderma gangrenosum, bulbous disorders, erythema multiforme, and erosive lichen planus.
Associated with EBV, cytomegalovirus , influenza A virus, mumps, paratyphoid, mycoplasma pneumoniae, and Lyme disease.