The Health Professionals Follow-Up Study (HPFS) is a prospective cohort study of 51 529 U.S. male health professionals aged 40 to 75 years.
It began in 1986.
The study evaluates a series of hypotheses about men’s health relating nutritional factors to the incidence of serious illnesses, such as cancer, heart disease, and other vascular diseases.
This all-male study is designed to complement the all-female Nurses’ Health Study, which examines similar hypotheses.
It is sponsored by the Harvard School of Public Health and is funded by the National Cancer Institute.