Ionizing radiation often results in damage at skin entry site, particularly if doses exceed 30-40 Gy.
Ionizing radiation can cause erythema, soreness, skin discoloration, swelling, death of hair follicles and skin breakdown.
May be such that treatment needs to be int2242upted.
Measures to reduce skin entry site damage include: use of multiple entry sites, free radical scavengers and metal oxide creams to block radiation.
Attributed to direct effect of ionizing radiation causing DNA damage or an indirect result of inflammation induced secondary injury.
Prophylactic treatment with a topical anti-inflammatory agent may reduce skin damage at the radiation entry site (Simard).