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Oxygen saturation gap

Describes differences between oxyhemoglobin percentage as measured by pulse oximetry (Spo2) or as estimated from arterial oxygen tension (Pao2) when compared with the oxyhemoglobin percentage (Sao2) as measured by co-oximetry.

May indicate the presence of methemoglobinemia.

May indicate the presence of poisoning with cyanide, carbon monoxide or hydrogen sulfide.

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