Prilosec trade name
Pregnancy category AU: B3
Routes of administration by mouth, intravenous
Drug class Proton-pump inhibitor, that works by blocking the release of stomach acid.
Bioavailability 35–76%
Protein binding 95%
Metabolism Liver (CYP2C19, CYP3A4)
Elimination half-life 1–1.2 hours
Excretion 80% (urine)
20% (bile via feces)
Omeprazole, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome.
It is also used to prevent upper gastrointestinal bleeding in people who are at high risk.
Omeprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to that of other PPIs.
Common side effects: nausea, vomiting, headaches, abdominal pain, and increased intestinal gas.
Serious side effects may include Clostridium difficile colitis, an increased risk of pneumonia, an increased risk of bone fractures, and the potential of masking stomach cancer.
Whether it is safe for use in pregnancy is unclear.