Nontricyclic heterocyclic antidepressant is utilized for smoking cessation.
Bupropion probably works by inhibiting reuptake of dopamine and nor-epinephrine increasing amounts of both neurotransmitters which bind to their receptors in the brain.
Bupropion may be useful for patients that do not tolerate tricyclic antidepressants.
Second and third line treatments for major depressive disorders.
Side effects include stimulant effects, tachycardia, insomnia, headaches, and seizure risk greater than other antidepressants.