Is a chronic relapsing disease, 50-80% of patients will have a recurrence within 6 to 12 months after discontinuation of therapy.
Accounts for 10% of upper G.I. bleeds.
Severe gastroesophageal reflux and alcohol abuse are the two most common risk factors for erosive esophagitis complicated by bleeding.
Other causes of esophagitis associated with bleeding include pill esophagitis and infectious esophagitis.
Rarely, ischemia may lead to esophageal necrosis.
Associated with oral bisphosphonates, usually when not taken appropriately.
Any inflammation or irritation of the esophagus.
Common causes include acid reflux, side effects of certain medications, and bacterial or viral infections.
Associated with a variety of symptoms that include:
trouble swallowing
sore throat
heartburn
When untreated can lead to ulcers, scarring, and severe narrowing of the esophagus.
Eosinophilic esophagitis is caused by too many eosinophils in the esophagus.
it is an over response to an allergen.
Common triggers include:
milk
soy
eggs
wheat
peanuts
tree nuts
shellfish
Inhaled allergens, such as pollen, can also contribute to this form of esophagitis.
Reflux esophagitis is usually result of gastroesophageal reflux disease (GERD).
Drug-induced esophagitis can occur when certain medications are taken without enough water, allowing medications to linger in the esophagus too long.
Such medications include:
pain relievers
antibiotics
potassium chloride
bisphosphonates
Infectious esophagitis is rare entity can due to bacteria, viruses, fungi, or parasites.
Infectious esophagitis is common in people with HIV or AIDS, cancer, and diabetes.
Symptoms of esophagitis:
difficulty swallowing
pain on swallowing
sore throat
hoarse voice
heartburn
acid reflux
chest pain
nausea
vomiting
epigastric abdominal pain
decrease in appetite
cough
Very young children may have difficulty feeding.
Risk factors for esophagitis:
weakened immune system due to HIV or AIDS
diabetes
leukemia/lymphoma
hiatal hernia
chemotherapy
radiation therapy of the chest
surgery in the chest area
medications
aspirin and anti-inflammatory medications
chronic vomiting
obesity
alcohol and cigarette use
a family history of allergies or esophagitis
Your chance of developing an infection of the esophagus is low if you have a healthy immune system.
Complications of esophagiitis include:
stricture, or narrowing, ulcers of the esophagus.
Evaluation includes:
endoscopy with biopsies
upper GI series
allergy testing
Management includes:
antiviral medications
antifungal medications
antacids
pain relievers
oral steroids
proton pump inhibitors
Elimination allergic trigger foods
avoiding spicy, acidic foods and drinks, and raw or hard foods.
avoiding tobacco and alcohol.
Esophageal dilation may be required
Refrain from lying down for 30 minutes after taking medications or food.
Endoscopic views of esophagitis grades. (A) Grade A—1 or more mucosal breaks no longer than 5 mm that do not extend between the tops of two mucosal folds.
(B) Grade B—1 or more mucosal breaks (arrow) longer than 5 mm that do not extend between the tops of two mucosal folds.
(C) Grade C—1 or more mucosal breaks (arrows) that are continuous between the tops of 2 or more mucosal folds, but involve less than 75% of the circumference.
(D) Grade D—1 or more mucosal breaks (arrows) that involve at least 75% of the esophageal circumference.