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Ceruloplasmin

A protein which is an acute phase reactant increasing with inflammation, infection and trauma.


Ceruloplasmin helps move iron from the organs and tissues of the body and prepares it for incorporation into a molecule called transferrin, which transports it to red blood cells to help carry oxygen. 


Ceruloplasmin  is involved in iron transport and processing. 


Ceruloplasmin is needed to transport copper around the blood, and with decreased synthesis results in copper deficiency in the brain, with neurological problems that generally appear in adulthood and worsen over time. 


Low levels in Wilson disease, newborn period, protein-losing enteropathy, and cirrhosis.

Required for mobilization of iron from reticuloendothelial cells to plasma.

Oxidizes ferrous iron to ferric form of iron that is required for iron binding by apotransferrin.

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